Theoretical Biology & Bioinformatics

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Kirsten ten Tusscher

Kirsten ten Tusscher

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Moret B, Marhava P, Aliaga Fandino AC, Hardtke CS, Ten Tusscher KH (2020).
Local auxin competition explains fragmented differentiation patterns.
Nature Communications doi: 10.1038/s41467-020-16803-7. Nature Communications.

Boer MD, Santos Teixeira J, Ten Tusscher KH (2020).
Modeling of Root Nitrate Responses Suggests Preferential Foraging Arises From the Integration of Demand, Supply and Local Presence Signals.
Front Plant Sci. doi: 10.3389/fpls.2020.00708. Front Plant Sci..

Salvi E, Rutten JP, Di Mambro R, Polverari L, Licursi V, Negri R, Dello Ioio R, Sabatini S, Ten Tusscher KH (2020).
A Self-Organized PLT/Auxin/ARR-B Network Controls the Dynamics of Root Zonation Development in Arabidopsis thaliana.
Dev Cell doi: 10.1111/pce.13977. Dev Cell.

van den Herik B, Bergonzi S, Bachem CWB, Ten Tusscher KH (2020).
Modeling the physiological relevance of sucrose export repression by an FT homolog in the long-distance phloem of potato.
Plant Cell Environ. doi: 10.1111/pce.13977. Plant Cell Environ..

Ten Tusscher KH (2020).
Of mice and plants: Comparative developmental systems biology.
Dev Biol. doi: 10.1016/j.ydbio.2018.10.024. Dev Biol..

Korver RA, van den Berg T, Meyer AJ, Galvan-Ampudia CS, Ten Tusscher KH,   Testerink C. (2020).
Halotropism requires phospholipase Dzeta1-mediated modulation of cellular polarity of auxin transport carriers.Of mice and plants: Comparative developmental systems biology.
Plant Cell Environ. doi: 10.1111/pce.13646. Plant Cell Environ..

Weise LD  Ten Tusscher KH (2020).
Discrete mechanical growth model for plant tissue.
PLoS One doi: 10.1371/journal.pone.0221059. PLoS One.

Santos Teixeira JA  Ten Tusscher KH (2019).
The Systems Biology of Lateral Root Formation: Connecting the Dots.
Mol Plant doi: 10.1016/j.molp.2019.03.015. Mol Plant.

Rutten, JA  Ten Tusscher KH (2019).
In Silico Roots: Room for Growth.
Trends Plant Sci. doi: 10.1016/j.tplants.2018.11.005 Trends Plant Sci..

Vroomans, RMA, Hogeweg P, Ten Tusscher KH (2018).
Around the clock: gradient shape and noise impact the evolution of oscillatory segmentation dynamics.
EvoDevo doi: 10.1186/s13227-018-0113-2. EvoDevo.

Vroomans, RMA  Ten Tusscher KH (2018).
Modeling evolution of developmental gene regulatory networks.
In Evolutionary Developmental Biology - A Reference Guide Springer.

van den Berg, T  Ten Tusscher KH (2017).
Auxin Information Processing; Partners and Interactions beyond the Usual Suspects.
Int J Mol Sci. pii: E2585. Int J Mol Sci..

Laskowski M  Ten Tusscher KH (2017).
Periodic lateral root priming, what makes it tick.
Plant Cell pii: tpc.00638.2016.. Plant Cell.

van den Berg T, Korver RA, Testerink CS,  Ten Tusscher KH (2016).
Modeling halotropism: A key role for root tip architecture and reflux loop remodeling in redistributing auxin.
Development , pii: dev.135111. Development.

Vroomans RM, Hogeweg P, Ten Tusscher KH. (2016).
In silico evo-devo: reconstructing stages in the evolution of animal segmentation.
Evodevo ,7: 14. Evodevo.

Kazbanov I.V., Tusscher K.   Panfilov A.V. (2016).
Effects of Heterogeneous Diffuse Fibrosis on Arrhythmia Dynamics and Mechanism.
Sci Rep , 20835. ScientificReports.

Vroomans R.M.A., Hogeweg P., Ten Tusscher K. (2015).
Segment-specific adhesion as a driver for convergent extension.
PLoS Computational Biology , e1004092. PLoSCompBiol.

Mahonen A.P., Ten Tusscher K., Siligato R., Smetana O., Diaz-Trivino S., Salojarvi J., Wachsman G., Prasad K., Heidstra R., Scheres B. (2014).
PLETHORA gradient formation mechanism separates auxin responses.
Nature , nature13663. Nature.

Van Berkel K., De Boer R.J., Scheres B. & Ten Tusscher K.H. (2013).
Polar auxin transport: models and mechanisms.
Development , 140: 2253-2268. Development. DownLoad PDF.

Ten Tusscher K.H. (2013).
Mechanisms and constraints shaping the evolution of body plan segmentation.
Eur Phys J E Soft Matter , 36: 54. Eur Phys J E Soft Matter. DownLoad PDF.

Ten Tusscher K.H. & Scheres B. (2011).
Joining forces: feedback and integration in plant development.
Curr Opin Genet Dev , 21: 799-805. Curr Opin Genet Dev. DownLoad PDF.

Ten Tusscher K.H. & Hogeweg P. (2011).
Evolution of Networks for Body Plan Patterning; Interplay of Modularity, Robustness and Evolvability.
Plos Comp Biol , 7: e1002208. Plos Comp Biol. DownLoad PDF.

Ten Tusscher K.H. & Hogeweg P. (2009).
The role of genome and gene regulatory network canalization in the evolution of multi-trait polymorphisms and sympatric speciation.
BMC Evol Biol , 9: 159. BMC Evol Biol. DownLoad PDF.

Ten Tusscher K.H.& Mourad A.& Nash M.P.& Clayton R.H.& Bradley C.P.& Paterson D.J.& Hren R.& Hayward M.& Panfilov A.V. & Taggart P. (2009).
Organization of ventricular fibrillation in the human heart: experiments and models.
Exp Physiol , 94: 553-562. MEDLINE.

Keldermann R.H. & Ten Tusscher K.H. & Nash M. P. & Bradley C.P & Paterson D.J & Hren R. & Hayward M. &, Panfilov A.V. & Taggart P.. (2009).
A computational study of mother rotor VF in the human ventricles.
Am.J.Physiol. , 296: H370-H379. MEDLINE.

Ten Tusscher K.H. & Panfilov A.V. (2008).
Modeling of the ventricular conduction system
PBMB , 96: 152-170. PBMB. DownLoad PDF.

Keldermann R.H. & Ten Tusscher K.H. & Nash M. P. & Hren R. & Taggart P & Panfilov A.V. (2007).
Effect of heterogeneous APD restitution on VF organization in a model of the human ventricles
Am.J.Physiol. , 294: H764-H474. MEDLINE. DownLoad PDF.

Ten Tusscher K.H. & Panfilov A.V. (2007).
Influence of diffuse fibrosis on wave propagation in human ventricular tissue
Europace , 9: vi38-vi45. Europace. DownLoad PDF.

Ten Tusscher K.H.& Hren R. & Panfilov A.V. (2007).
Organization of Ventricular Fibrillation in the Human Heart
Circ. Res. , 100: e87-e101. MEDLINE. DownLoad PDF.

Ten Tusscher K.H. & Panfilov A.V. (2006).
Cell model for efficient simulation of wave propagation in human ventricular tissue under normal and pathological conditions.
Phys. Med.Biol., 51: 6141-6156. PMB. DownLoad PDF.

Ten Tusscher K.H. & Panfilov A.V. (2006).
Alternans and spiral breakup in a human ventricular tissue model.
Am.J.Physiol., 90: 326-345. MEDLINE. DownLoad PDF.

Ten Tusscher K.H.& Bernus O.& Hren R. & Panfilov A.V. (2006).
Comparison of electrophysiological models for human ventricular cells and tissues.
Prog Biophys Mol Biol., 90: 326-345. MEDLINE. DownLoad PDF.

Ten Tusscher K.H. & Panfilov A.V. (2005).
Wave propagation in excitable media with randomly distributed obstacles.
Multiscale Model. Simul., 3: 265-282. DownLoad PDF.

Ten Tusscher K.H.& Noble D.& Noble P.J. & Panfilov A.V. (2004).
A model for human ventricular tissue.
Am.J.Physiol., 286: 1573-1589. MEDLINE. DownLoad PDF.

Ten Tusscher K.H. & Panfilov A.V. (2004).
Eikonal formulation of the minimal principle for scroll wave filaments.
Phys. Rev. Lett, 93: 108106. MEDLINE. DownLoad PDF.

Ten Tusscher K.H. & Panfilov A.V. (2003).
Influence of nonexcitable cells on spiral breakup in two-dimensional and three-dimensional excitable media.
Phys Rev E Stat Nonlin Soft Matter Phys., 68: 062902. MEDLINE. DownLoad PDF.

Ten Tusscher K.H. & Panfilov A.V. (2003).
Reentry in heterogeneous cardiac tissue described by the Luo-Rudy ventricular action potential model.
Am.J.Physiol., 284: H542-H548. MEDLINE. DownLoad PDF.