Prof. dr. Paulien Hogeweg
Bioinformatics group, Utrecht University
3584 CH Utrecht
phone: +31 30 2533692
fax: +31 30 2513655
email: user: P.Hogeweg domain: uu.nl
The aim of my research is to understand biotic systems as
dynamic information processing systems at many interconnected levels.
In the seventies we identified the study of informatic processes in biotic systems as an open and promising research area for which we coined the
term Bioinformatics .
Within this framework my current research focuses on evolutionary dynamics
Our research on multilevel evolution aims to understand how different levels of selection, complex genotype phenotype mapping, and interactions over different timescales contribute to the evolution of complexity at the level of individuals and/or ecosystems. A central conjecture of our current research is that spatial pattern formation, and therewith selection pressures at multiple timescales is a prerequisite for evolving complex regulatory individuals. We are now investigating this conjecture focusing on mutual interactions between
My research on (evolution of) morphogenesis
focuses on the interaction between genetic (informatic)
and dynamic processes. We use (and further develop) a powerful method
for multi-scale modeling (CPM). This allows us to study morphogenesis in the literary
sense as opposed to many developmental models which only consider pattern formation. Apart from developing models of specific developmental processes
we study morphogenetic mechanisms which arise 'de-novo' in evolutionary models.
Computational Biology course
Publications since 2010
Publications before 2010
Picturesque summary of recent results of the group,
made on the occasion of "30 years Bioinformatics"